stimulantEVIDENCEBUSOTC
Yohimbine
Alkaloid from Pausinystalia yohimbe bark. Alpha-2 adrenergic antagonist. Increases norepinephrine. Used for fat loss, libido, and acute focus.
Dose range2.5–10mg
Half-life0.5h
Onset20min
Safety2/5medium evidence base
Mechanism of action
Alpha-2 adrenergic receptor antagonist. Removes negative feedback on norepinephrine release, increasing sympathetic tone.
Benefits
Increased lipolysis (fasted)
EVIDENCEBMultiple RCTs.
Erectile dysfunction
EVIDENCEBOlder RCTs.
Side effects
- Anxiety / paniccommonmoderate
- Hypertensioncommonmoderate
- Tachycardiacommonmoderate
Where to buy
Affiliate linksNo vendor products listed yet. Vendors — list a product.