vitaminEVIDENCEBUSOTC
Vitamin K2 (MK-7)
aka Menaquinone-7 · MK-7
MK-7 form has longest half-life and best cardiovascular evidence. Pair with vitamin D3.
Dose range0.05–0.18mg
Half-life—h
Onset—min
Safety5/5high evidence base
Mechanism of action
Cofactor for gamma-carboxylation. Activates matrix Gla-protein (vascular calcium handling) and osteocalcin (bone matrix).
Benefits
Cardiovascular health (arterial calcification)
EVIDENCEBKnapen 2015.
Bone density (postmenopausal)
EVIDENCEBMultiple RCTs.
Side effects
- Interactions with warfarincommonmoderate
Where to buy
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