neuroprotectiveEVIDENCEBUSOTC
Resveratrol
Polyphenol from grape skins and Japanese knotweed. SIRT1 activator. Studied for longevity and cardiovascular health.
Dose range250–500mg
Half-life9h
Onset—min
Safety5/5medium evidence base
Mechanism of action
Activates SIRT1 (longevity pathway). Antioxidant. May potentiate NR/NMN via sirtuin co-activation.
Benefits
Endothelial function
EVIDENCEBMultiple RCTs.
Insulin sensitivity
EVIDENCECMixed evidence.
Side effects
- Mild blood thinninguncommonmild
Where to buy
Affiliate links| Vendor | Product | Size | Price | Per unit | |
|---|---|---|---|---|---|
| Double Wood Supplements 4.4 | Trans-Resveratrol, 60ct (500mg) | 60 × 500mg | $24.99 | $0.42 | Buy |