adaptogenEVIDENCECUSOTC

Muira Puama

aka Ptychopetalum olacoides · Marapuama

Amazonian root (Ptychopetalum olacoides) traditionally used for libido and cognitive support. Limited Western evidence.

Dose range1000–1500mg

Half-life—h

Onset—min

Safety4/5low evidence base

Mechanism of action

Multiple bioactive compounds including alkaloids, lupeol, beta-sitosterol. Animal studies suggest cholinergic enhancement and dopaminergic activity. Human evidence is sparse — most clinical claims come from small French trials in the 1990s.

History

Muira puama has been used by Amazon indigenous peoples for centuries for vitality, sexual function, and nervous system complaints. Western interest accelerated in the 1990s through French studies (Waynberg) on libido and sexual function. The compound is unscheduled globally but the evidence base for specific claims is weak.

Benefits

Libido (male and female)
EVIDENCEC
Waynberg 1994 small trials.
Mood and cognitive function
EVIDENCEC
Animal models.

Side effects

Insomnia (high dose)uncommonmild

Cited research

Muira puama for sexual function (Waynberg)1994
PMID 8050019 ↗
Ptychopetalum olacoides neuropharmacology (da Silva)2004
PMID 15046796 ↗

Where to buy

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Vendor	Product	Size	Price	Per unit
Nootropics DepotFeatured 4.8	Muira Puama — Nootropics Depot	—	See vendor	—	Shop Ad
Double Wood Supplements 4.4	Muira Puama — Double Wood	—	See vendor	—	Shop Ad
Amazon Marketplace 3.5	Muira Puama — Amazon	—	See vendor	—	Shop Ad
iHerb 4.2	Muira Puama — iHerb	—	See vendor	—	Shop Ad

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