stimulantEVIDENCEAUSSchedule II
Methylphenidate
aka Ritalin · Concerta · Methylin
Prescription stimulant for ADHD (Ritalin, Concerta). Increases dopamine and norepinephrine.
Dose range5–40mg
Half-life3h
Onset30min
Safety3/5high evidence base
Mechanism of action
Dopamine and norepinephrine reuptake inhibitor (DAT/NET). Increases extracellular DA/NE in PFC.
Benefits
ADHD symptoms
EVIDENCEAHundreds of RCTs.
Acute focus in non-ADHD
EVIDENCEABattleday 2015.
Side effects
- Insomniacommonmoderate
- Appetite suppressioncommonmoderate
- CV stresscommonmoderate
- Abuse potentialcommonsevere
Where to buy
Affiliate linksNo vendor products listed yet. Vendors — list a product.