amino-acidEVIDENCEBUSOTC
Glycine
Smallest amino acid, inhibitory neurotransmitter and sleep enhancer. NMDA co-agonist.
Dose range3000–5000mg
Half-life1h
Onset—min
Safety5/5medium evidence base
Mechanism of action
Direct inhibitory neurotransmitter at glycine receptors (brainstem, spinal cord). Co-agonist at NMDA receptor glycine site.
Benefits
Sleep quality at bedtime
EVIDENCEBYamadera 2007.
Reduced subjective fatigue
EVIDENCEBBannai 2012.
Side effects
- Mild GI upset (high dose)raremild
Where to buy
Affiliate links| Vendor | Product | Size | Price | Per unit | |
|---|---|---|---|---|---|
| Double Wood Supplements 4.4 | Glycine Powder, 250g | — | $14.99 | — | Buy |