neuroprotectiveEVIDENCEAUSOTC
CoQ10
aka Coenzyme Q10 · Ubiquinone · Ubiquinol
Mitochondrial electron-transport cofactor. Naturally declines with age. Ubiquinol form is the active reduced state.
Dose range100–300mg
Half-life33h
Onset—min
Safety5/5high evidence base
Mechanism of action
Cofactor in mitochondrial electron transport chain (complexes I-III). Antioxidant. Declines with statin use and aging.
Benefits
Statin-induced myalgia
EVIDENCEBBanach 2015 meta-analysis.
Cardiovascular outcomes in HF
EVIDENCEAQ-SYMBIO trial.
Side effects
- Mild GI upsetraremild
Where to buy
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