neuroprotectiveEVIDENCEBUSOTC

Chlorella

aka Chlorella vulgaris · Chlorella pyrenoidosa

Single-celled green algae. Heavy-metal binding, nutritional density, immune support. The cell wall must be cracked for nutrient absorption.

Dose range1500–5000mg

Half-life—h

Onset—min

Safety4/5medium evidence base

Mechanism of action

High chlorophyll content with metal-chelating properties. Polysaccharide cell wall components have immunomodulating effects. Complete protein and B-vitamin content provide nutritional support. The chlorella cell wall is naturally tough; commercial products crack the wall mechanically to enable nutrient absorption.

History

Chlorella was identified in the 19th century but commercial cultivation became practical in the 1960s. Japanese research led the modern clinical interest. Multiple small RCTs support various claims. The heavy metal detoxification claims are partly supported but often overstated in marketing. Unscheduled globally.

Benefits

Cardiovascular markers
EVIDENCEB
Multiple trials.
Immune function
EVIDENCEB
Multiple small trials.
Heavy metal mobilization (mercury)
EVIDENCEC
Animal models + small trials.

Side effects

GI upsetcommonmild
Photosensitivity (rare)raremoderate

Cited research

Chlorella for cardiovascular and metabolic markers (Ebrahimi-Mameghani)2017
PMID 28395725 ↗
Chlorella for immune function (Kwak)2012
PMID 22682109 ↗
Chlorella for heavy metal detoxification (Uchikawa)2011
PMID 21088277 ↗

Where to buy

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Vendor	Product	Size	Price	Per unit
Nootropics DepotFeatured 4.8	Chlorella — Nootropics Depot	—	See vendor	—	Shop Ad
Life Extension 4.3	Chlorella — Life Extension	—	See vendor	—	Shop Ad
Double Wood Supplements 4.4	Chlorella — Double Wood	—	See vendor	—	Shop Ad
Amazon Marketplace 3.5	Chlorella — Amazon	—	See vendor	—	Shop Ad

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