cholinergicEVIDENCEAUSOTC
CDP-Choline
aka Citicoline · Cognizin
Naturally occurring compound serving as both a choline and uridine source. Extensive clinical evidence for memory and stroke recovery.
Dose range250–500mg
Half-life56h
Onset60min
Safety5/5high evidence base
Mechanism of action
Hydrolyzed into choline and cytidine. Choline → ACh; cytidine → uridine → synaptic membrane synthesis. Increases dopamine receptor density.
Benefits
Memory and attention
EVIDENCEAAlvarez et al. 1997.
Stroke recovery
EVIDENCEAICTUS trial, Davalos 2002.
Side effects
- Mild GI upsetraremild
Where to buy
Affiliate links| Vendor | Product | Size | Price | Per unit | |
|---|---|---|---|---|---|
| Nootropics DepotFeatured 4.8 | CDP-Choline (Citicoline) Capsules, 60ct (300mg) | 60 × 300mg | $29.99 | $0.50 | Buy |
| Double Wood Supplements 4.4 | Citicoline Capsules, 60ct (250mg) | 60 × 250mg | $19.99 | $0.33 | Buy |
| Pure Nootropics 4.5 | Citicoline (CDP-Choline) Capsules, 60ct (300mg) | 60 × 300mg | $29.99 | $0.50 | Buy |