The effect of piracetam on the behavior of
Nauphoeta cinerea cockroaches in an open field
by
Inozemtsev AN, Tselkova NV,
Bernui LK, Zhuzhikov DP, Tushmalova NA.
Lomonosov State University, Moscow.
Zh Vyssh Nerv Deiat Im I P Pavlova 1998 Mar-Apr;48(2):260-6
ABSTRACT
For 30 min the behaviour of 164 male cockroaches was
studied in an "open field" analog. At the 31st min the electrical light
was switched on and the examination was continued for 10 min. It was found
out that the insects placed in the "open field" and subjected to a sudden
illumination behaved in a similar way. After the initial freezing a sharp
increase in the motor activity was observed with subsequent habituation.
Per os administration of 200-400 mg/kg of piracetam (a solution of 5 mg
of the drug and 500 mg of honey in 5 ml of water) did not change the freezing
period but accelerated habituation and decreased the locomotion augmentation
caused by the light. The obtained data suggest that piracetam improves memory
and non-associative learning and exerts a stress-protective effect on cockroaches.
Piracetam
Idebenone
Vinpocetine
Vasopressin
Desmopressin
Meclofenoxate
New brain cells
Centrophenoxine
The memory switch?
Dumb-drug euphoria
Piracetam (Nootropil)
Pyrrolidone derivatives
Growing new brain cells
Piracetam and dopamine
Piracetam as an anxiolytic
Piracetam and working memory
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